Second Generation PCI Express spreading roots

According to Jag Bolaria of the Linley Group, the 5 Gbps version of PCI Express has moved beyond PC applications into embedded systems and networking.  In his article in DesignLine, we learn that PCIe Gen2 channels are limited to about a length of 10 inches (without connectors or vias)

Take a look:
PCI Express goes everywhere

Are you running up against these sorts of constraints in your PCIe 2.0 designs?  Have you looked into using the Channel Analysis features in Allegro PCB SI GXL to validate your channel design before prototyping?