Deactivate/disable components/instances in Cadence Schematic

Is there any way to temporarily deactivate or disable an instance in Cadence Virtuoso Schematic Editor so that it won't be simulated? I am migrating from Agilent ADS to Cadence and cannot find this useful function. I need to debug my circuit. Being able to quickly enable/disable instances would help a lot. Searched in google and cannot find anything useful. Does anybody know about it? Thanks a lot!